Vaccine Adjuvants: Immunological and Clinical Principles...

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Vaccine Adjuvants: Immunological and Clinical Principles (Infectious Disease)

Name: Vaccine Adjuvants: Immunological and Clinical Principles (Infectious Disease)
ISBN: 9781592599707

Charles J. Hackett, Donald A. Harn Jr

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A cutting-edge review of the major research areas of adjuvant discovery, design, development, and use. The authors lay down a rational basis for vaccine adjuvant function and analyze a number of significantly distinct adjuvant-active molecules to illuminate the principles of their function and use. The focus is on specific receptor-ligand interactions, including the molecular features needed for a compound to possess adjuvant activity. The critical interface zone between the innate and adaptive immune systems is also analyzed to show how adjuvants exert their effects on T- and B-cell activation. Additional chapters address the possibility of tailoring adjuvants to yield optimally safe and effective responses.

კატეგორია:

Medicine

წელი:

2005

გამომცემლობა:

Humana

ენა:

english

გვერდები:

260

ISBN 10:

1592599702